Portsmouth, NH

Commercial Real Estate for Sale in Portsmouth NH

13Results

Take a look at the latest commercial properties on the market in Portsmouth, New Hampshire. Contact Portside Real Estate Group for further information or to schedule a tour. Remember to sign up for an account to save your favorite properties and receive alerts on new listings.

Newest
New Listing
278 Lafayette Road Portsmouth NH 03801

$180,000

Portsmouth, NH

278 Lafayette Road

  • 1985 Year Built
  • 16 Days on Market
MLS#: 5097457
New Listing

$1,300,000

Portsmouth, NH

3601 Lafayette Road

  • 4.5 Acres
  • 2,615 SqFt
  • 24 Days on Market
MLS#: 5095981

$550,000

Portsmouth, NH

330 Borthwick Avenue

  • 1986 Year Built
  • 35 Days on Market
MLS#: 5094209

$3,440,000

Portsmouth, NH

54 Maplewood Avenue

  • 2019 Year Built
  • 51 Days on Market
MLS#: 5090820

$249,000

Portsmouth, NH

6 Greenleaf Woods Drive

  • 1987 Year Built
  • 72 Days on Market
MLS#: 5087061

$450,000

Portsmouth, NH

118 Maplewood Avenue

  • 1990 Year Built
  • 85 Days on Market
MLS#: 5084873

$12,500,000

Portsmouth, NH

40 Congress Street

  • 1878 Year Built
  • 86 Days on Market
MLS#: 5084657

$950,000

Portsmouth, NH

2425 Lafayette Road

  • 1900 Year Built
  • 0.19 Acres
  • 4,080 SqFt
  • 108 Days on Market
MLS#: 5081248

$825,000

Portsmouth, NH

930 Route 1 Bypass

  • 167 Days on Market
MLS#: 5075314

$3,300,000

Portsmouth, NH

144 Washington Street

  • 1747 Year Built
  • 0.25 Acres
  • 3,034 SqFt
  • 211 Days on Market
MLS#: 5072167

$715,000

Portsmouth, NH

135 Market Street

  • 1850 Year Built
  • 497 Days on Market
MLS#: 5031265

$149,000

Portsmouth, NH

175 High Street

  • 555 Days on Market
MLS#: 5025980

Portsmouth NH Commercial Real Estate for Sale

Commercial real estate in Portsmouth benefits from strong foot traffic, a thriving tourism sector, and a strategic location along the New Hampshire Seacoast. Listings may include retail storefronts near Market Square, office space in mixed-use developments, and hospitality properties positioned close to the waterfront and major highways. 

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Copyright 2026 PrimeMLS, Inc. All rights reserved. This information is deemed reliable, but not guaranteed. The data relating to real estate displayed on this display comes in part from the IDX Program of PrimeMLS. The information being provided is for consumers’ personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Data last updated July 16, 2026 1:40 PM EDT